Conference Schedule
September 19-20, 2006
Please visit us at the Meeting the Biotechnology Challenge in Iowa conference
to be held at the new Marriott Hotel and conference center in Coralville, IA.
October 10-12, 2006
Please join us again this year at The Annual Meeting of
The American Society of Human Genetics (ASHG) in New Orleans, Louisiana.
Booth #329
We look forward to seeing you there!
>> Meeting website
Thanks to those who visited us at our recent BioResearch Product Faires at the Mayo Clinic
(July 19th, 2006) and University of Michigan (July 27th, 2006).
If you didn't get the opportunity to visit us, please view our
conference schedule for more opportunities to meet
us or you may contact us to set up a private meeting.
Custom Designed Software
"Precisely What You Need."
Do you wish to improve the speed and reliability of your research?
Get precisely what you need from experts with more than 40 years of
experience in bioinformatics.
Our team can provide the bioinformatics support you need to take
your research to the next level.
>> More information
Tom's Word
I am proud to be asked to open this first newsletter with a few words about the growing excitement surrounding the release of our first 2 products -- Bio::POD and Bio::WebLab. The release of Bio::POD in January brought an extremely valuable tool to the scientific community. For over 5 years the research version of this genome/transcriptome browser and amplimer ordering tool has been an integral part of gene screening efforts at the University of Iowa. In the coming months as WebLab is released, the same tools that allow the management of complex screening projects in our research environment will be made available as well.
It has been a delight to see these highly robust commercial versions of research prototypes come to fruition. The quality of the interfaces, underlying implementation, and documentation is the realization of my hopes in the co-founding of Bio::Neos. As large-scale genechip-based projects produce more and more hypotheses about the functions of genes and their roles in pathways, it will become more and more necessary to manage large multi-locus projects with this software. I encourage you to contact Bio::Neos to arrange a demonstration of these products.
The Pubs
Recommended readings from the Bio::Neos team:
Prioritizing regions of candidate genes for efficient mutation screening
by Braun et al. Published in Human Mutation February 2006.
If you haven't read this article yet, we recommend you take a look. It is a quick
read and is foundational to our Bio::POD software solution.
A high-resolution multistrain haplotype analysis of laboratory mouse genome
reveals three distinctive genetic variation patterns.
by Zhang et al. Published in Genome Research February 2005.
This paper provides excellent insight into the use of mice for studying complex
human diseases.
Bio::POD Testimonial
Bio::POD has significantly increased the efficiency and effectiveness of candidate gene screening in our lab. Prior to Bio::POD there would be four or five web pages that one would need to visit in order to gather data on a new candidate gene. With Bio::POD we can enter an accession number for the gene of interest and Bio::POD will informatically retrieve data from multiple web pages and display the information in a user-friendly format. Being able to visualize the entire gene structure in one window makes picking primers more efficient. We can pick primers with one key-stroke by simply hi-lighting the portion of the gene that we want to amplify.
One of the most exciting features of Bio::POD is the prioritized annotated region algorithm (PAR). PAR uses information about the gene structure, functional regions of the protein product and conservation information to predict the regions of the genes that are most likely to harbor disease-causing mutations. Armed with the knowledge of PAR we have the advantage of screening the most important portions of candidate genes, and are able to screen far more genes in a shorter period of time.
Custom Design Software Testimonial
The Department of Ophthalmology and Visual Science at the University of Iowa has amassed a large collection of visual data from its patients in the form of 35mm slides. As available computational power increases, the advantages of transferring that data into a digital format have become increasingly obvious. However, the size of our collection of slides and negatives is in excess of two million, making the digitization task a difficult project. We quickly realized that the bottleneck in this process is the association of patient information and other data with each slide. Because of the custom nature of this digitization project, we knew that we would need custom developed software in order to increase our efficiency. Bio::Neos met with us, quickly familiarized themselves with the project, and developed software that specifically met our needs. With Bio::Neos developing software for us, we were able to avoid the Human Resources headaches of hiring and training a new employee. I have been using the software for several months without any major problems, and any questions or concerns that I do have are promptly addressed by Bio::Neos staff. I couldn't be happier with the software. Bio::Neos did such a good job that we started a second phase of development for the software to add more features and capabilities.
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